The objective in the examine was to find out when, right after tadalafil dosing, no apparent blood pressure level interaction was observed. On this research, a significant interaction in between tadalafil and NTG was observed at Every single timepoint nearly and together with 24 hrs. At forty eight hrs, by most hemodynamic measures, the conversation concerning tadalafil and NTG was not noticed, Even though some far more tadalafil topics in comparison to placebo expert better blood-strain reducing at this timepoint. Right after 48 several hours, the interaction was not detectable (see Figure one).
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